“Be a voice, not an echo!” Korea University’s 112th commencement ceremony Korea University held its 112th commencement ceremony in the Tiger Dome at 10 a.m. on Monday, February 25, 2019. A total of 6,182 students—4,161 undergraduate and 2,021 graduate students—received their degrees at the ceremony. President Jaeho Yeom said in his congratulatory remarks, “This is the first year where we’ll have freshmen who were born in the 21st century. For the past four years as the president of Korea University, I’ve been making various efforts to better our education system. As Albert Einstein said, ‘imagination is more important than knowledge.’ I have been working on turning KU campus into a knowledge amusement park, which can serve as an incubator of imagination rather than just a place of knowledge transfer, by offering various creative places on campus, such as π-Ville, CCL, and Maker’s Space. Those of you who graduate today will be the first generation who witnessed the transformation of Korea University. I will finish my term as the 19th president of Korea University soon. I’m proud of how far we’ve come in our endeavor to innovate Korea University as the university of the future.” He added, “Wayne Gretzky, a Canadian ice-hockey hero, said ‘I skate to where the puck is going to be, not where it has been.’ We should be able to predict where 21st-century society is going to be. We’re heading toward the new normal. This change is irreversible. This is the default future—no one can change or deny this fact. What is important is that we should prepare ourselves to craft the future rather than react to it. So today, I’d like to share my thoughts on how proud you should be as the alumni of Korea University and how to prepare for the new normal.” He also remarked that “in 1905 when the country was on the verge of losing its national sovereignty to colonial powers, Korea University was founded under the spirit of ‘national salvation through education.’ It was the first higher education institution that taught modern studies, including law and economics, and was a private one funded by over 2,500 people across the country who voluntarily donated money and even their gold and silver accessories. Korean people’s yearning for taking their country back by cultivating talents through higher education made it possible to establish Korea University. KU alumni should never forget this history and always have a sense of responsibility to the society. Those of you who will receive diplomas today should also keep in mind the values of Liberty, Justice, and Truth and put your knowledge and skills in good use in the society.” President Yeom continued, “I’d like to emphasize that humankind has never stopped pioneering and improving the world. Challenge spirit and pioneer spirit are ever more important in the new normal of the 21st century. There will be failures and frustrations. But without difficulties, there is no rosy future. So far, you’ve been trying to live up to your family’s expectations, and you’ve been living as a model student of the 20th century-style education system. You’ve been educated to get good grades and survive fierce competition. You may find yourself more comfortable following what others say to you rather than trying things in an unfamiliar and unique way. But what I’d like to say to you is, be a voice, not an echo. One of the reasons why Korea University has been playing a pivotal role in our society is that KU alumni have made their voice heard in the society. They played a leading role in Korea’s democratization and industrialization processes. It is now your turn to play a leading role in shaping the 21st century with your own voice.” The Chairman of the Korea University Foundation Jae Ho Kim said in his congratulatory remarks that “You’ve learned what you need to become the leaders of Korea and the world. To become a true global leader, you should dream big. You need to be hungry to put your heart and soul into achieving your dream. Your dream will come true if you have the will to make it happen.” He added, “The world is waiting for your brave challenges. Think differently, be the first one to explore uncharted waters, and aim higher. You may face unexpected challenges along the way. But you can overcome these challenges and make a brighter future if you remind yourself of the never-give-in spirit of Korea University. The Chief Vice-chairman of the KU Alumni Association In Kim remarked, “You’ll go into the world where the fourth industrial revolution is taking place. You’re excellent talents who are qualified to become the global leaders of this new world. You can achieve your dream.” He advised the graduates to continue to move toward their dreams regardless of circumstances, while showing their steadfast loyalty to their alma mater and serving the communities to which they belong. The founder and CEO of L&P Cosmetics, Oh-sub Kwon, also delivered his congratulations to the graduates. He began by saying he was honored to speak at the commencement ceremony of his alma mater. “I went into the cosmetic business in 1996 after 12 years in academia. I failed big time twice before establishing my company 10 years ago thanks to the success of Mediheal, a face mask brand. You need to fail well if you want to succeed well. From now on, you’ll fail more times than you succeed. But never give up and fight for your dreams with a defiant and creative attitude,” he remarked. He also said that, “While writing this speech, I thought it would be a good idea to share a song of my life.” He went on to talk about ‘My Dream’, a song by Chi-hwan Ahn. He remarked, “What is your dream? Think of your long-cherished dream. Think of what you did to achieve the dream. You have a whole world ahead of you, a world with full of challenges and uncertainties. But remember, you’re never alone,” emphasizing that their 330,000 fellow alumni would be with them all the way and advised them once again not to give up on their dreams. That day, he donated KRW 100 million to a scholarship for the rugby team of Korea University, adding to the KRW 1 billion he had donated to the university for the development of sports last September. In accordance with his wishes, Korea University is actively supporting athletes on campus. Kwon has demonstrated consistent interest in supporting KU students since 2011, contributing academic scholarships, education funds for purchasing research aids, scholarships for international students, and College of Natural Science building construction project fund, which total at around 14.4 billion won. Since 2017, he has donated 30,000 sheets of Mediheal, the famous face mask from L&P Cosmetics, to KU students at the annual Korea-Yonsei Games. Daseul Sohn (’15, Division of Business Administration) delivered her valedictorian speech. She started her speech by saying, “The word ‘graduation’ will remind me of my college days.” Sohn said, “I will be a proud alumna of Korea University, keeping in mind the KU values of Liberty, Justice, and Truth.” She also remarked that “I’ll never forget all the guests who attended this meaningful event, great professors who taught us, and the alumni who supported us. We’ll be leaving this campus behind and joining the real society, but our sense of belonging to Korea University will forever bind our hearts together.”
Causes of early-onset gastric cancer occurring around 40s identified! Increased research on diagnosis and therapy of early-onset gastric cancer anticipated. ▲ Professor Sang-Won Lee (left) and Ph.D. student Dong-Gi Mun (right) Professor Sang-Won Lee’s research team of the Center for Proteogenome Research at Korea University has identified the causes of early-onset gastric cancer through a proteogenomic study conducted with early-onset gastric cancer patients. * Early-onset gastric cancer: Gastric cancer occurring in patients in their 40s or younger. * Proteogenomics: Comprehensive analytical research on the extensive genome and proteome using patients’ disease tissue samples. Professor Sang-Won Lee’s research team of the Center for Proteogenome Research at Korea University, supported by the Korea Post-Genome Project of the Ministry of Science and ICT (MSIT), published the research result in Cancer Cell (IF=22.84), the top academic journal in the field of cancer research, in the online edition of January 14 (morning, January 15, KST). * Title of Article: Proteogenomic Characterization of Human Early-Onset Gastric Cancer * Author Information: Daehee Hwang (Professor in the Department of New Biology, DGIST), Sang-Won Lee (Professor in the Department of Chemistry, Korea University), Sanghyuk Lee (Department of Life Science, Ewha Womans University), Eunok Paek (Department of Computer Science and Engineering, Hanyang University), Hark Kyun Kim (National Cancer Center), Eun Gyeong Yang (Biomedical Research Institute, Korea Institute of Science and Technology) (The aforementioned are corresponding authors with equal contribution.), Dong-Gi Mun (Ph.D. student in the Department of Chemistry, Korea University), Jinhyuk Bhin (Ph.D. in the Department of New Biology, DGIST), Sangok Kim (Ph.D. student in the Department of Life Science, Ewha Womans University), Hyunwoo Kim (Ph.D. in the Department of Computer Science and Engineering, Hanyang University), Jae Hun Jung (Ph.D. student in the Department of Applied Chemistry, Kyung Hee University), and others. Gastric cancer, a common cancer worldwide, is a fatal disease responsible for over 700,000 deaths a year and its mortality rate is the third highest for cancers after lung cancer and liver cancer. Gastric cancer rarely occurs before the 30s, and its onset is usually between the 40s and 70s as its incidence rate increases with the age. Early-onset gastric cancer refers to gastric cancer of which the onset is around the 40s. In Korea, the proportion of early-onset gastric cancer patients is about 15% of all gastric cancer patients, a figure higher than that of other countries. Early-onset gastric cancer is caused more by genetic factors than environmental factors. The risk of onset is higher in those who have a family history, and higher in women than in men. Early-onset gastric cancer occurring in young populations is often of the diffuse type, which is difficult to treat since it is diagnosed late, progresses rapidly, and is highly metastatic. The causes of early-onset gastric cancer had not been previously identified. * The diffuse type refers to a type of gastric cancer where the cancer tissues are diffused under the gastric mucosa, rather than existing as a cancerous mass. Therefore, this diffuse type gives no signs, is thus difficult to diagnose by endoscopy, and has a high mortality rate. Through joint research with many Korean basic science researchers and gastric cancer clinical researchers, the research group performed a proteomic analysis of the cancer tissues and surrounding normal tissues obtained from 80 early-onset gastric cancer patients over 5 years using a method known as next generation sequencing (NGS). As a result, the research group was able to identify the mutated genes correlated with the onset of early-onset gastric cancer (CDH1, ARID1A, RHOA) from about 7,000 somatic mutated genes, and showed that these genes are involved in the signaling pathways significantly related to the onset of early-onset gastric cancer. In addition, the genetic analysis of the tissues from the 80 gastric cancer patients showed that the gastric cancer is divided into four subtypes, each exhibiting different therapeutic responses. The research group found that the four gastric cancer subtypes each have different cell signaling pathways, and this discovery enables more precisely targeted searches for the causes of gastric cancer. Professor Sang-Won Lee, who participated in the research, explained its significance: “With the incidence rate of early-onset gastric cancer increasing in Korea, especially in the female population, this study identified the precise genetic causes of early-onset gastric cancer and is expected to trigger active research into the development of precise diagnoses and improved gastric cancer therapy.” [Terminology] 1. Cancer Cell ㅇ An internationally authoritative academic journal in the field of cancer research ※ Impact factor: 22.84 2. Proteogenomics ㅇ A convergence technology integrating genome-proteome information technology. Proteogenomics is a multi-omics technology for discovering and identifying biomolecular signatures significant to diseases by systematically integrating genomic and proteomic information. 3. Early-onset gastric cancer ㅇ Gastric cancer occurring in young populations in their 40s or younger. Early-onset gastric cancer accounts for 15% of the gastric cancers in Korea. The incidence rate is particularly high in young women. The incidence rate of early-onset gastric cancer is also increasing in the US. Early-onset gastric cancer is life threatening because it is typically of the diffuse type with extensively diffused small-sized cancer masses and thus difficult to discover and highly metastatic. 4. Cancer subtypes ㅇCancers are divided into subtypes according to the characteristics of their cancer cells, namely their microscopic morphology, the specific substances contained within them, or the specific changes found in their DNA. Given the additional results available from proteogenomics, cancers can now be divided into more precise subtypes by integrating the changes found in specific genomes and specific proteomes. 5. RNA and mRNA ㅇ RNA: Genetic molecules existing in the cell nucleus and cytoplasm and involved in protein synthesis. ㅇ mRNA: A specific type of RNA that transfers the genetic information from DNA to ribosomes where proteins are synthesized. 6. Proteome: The entire set of proteins existing in cells. 7. Multi-omics ㅇ Studies of the genome, transcriptome, proteome, metabolome, epigenome, and lipidome in our cells are respectively called “-omics,“ and the studies combining at least two “-omics“ are called “multi-omics.“ 8. Biomolecular signature ㅇ The collection of gene and protein attributes, such as DNA/RNA mutations, protein sequence mutations, protein expression and the modifications, that allow molecular measurement of disease states. 9. Diffuse type and intestinal type ㅇ About half of the gastric cancers found in Korean patients are classified microscopically as the diffuse type in which the cancer cells, rather than being clustered together, are extensively diffused. By contrast, the cancer cells of the intestinal type are clustered together and the cancer tissues can be identified microscopically. [Figure Description] ■Gene mutations related to the disease were identified in the genome of the early-onset gastric cancer patients. Figure 1. Proteogenomic analysis of nonsynonymous somatic mutation A) Significant mutated genes found in the early-onset gastric cancer patients (CDH1, TP53, BANP, MUC5B, RHOA, ARID1A). B) CDH1, ARID1A, and RHOA showing a high correlation with phosphorylation. ■The correlation of the proteogenome related to early-onset gastric cancer with cancer onset was analyzed. Figure 2. Quantitative analysis of mRNA-proteome correlation A) The analysis of the correlation between mRNA and proteome showed a 34.3% correlation. B) The analysis of the functions of the genes having a low correlation and a high correlation showed that the genes are involved in different signaling pathways. ■The analysis of the proteogenome of the 80 early-onset gastric cancer patients showed that the gastric cancer is divided into four subtypes. Figure 3. Subtypes of early-onset gastric cancer identified by proteogenomic analysis ■The genomic analysis of the four subtypes of early-onset gastric cancer identified distinct signaling pathways. Figure 4. Major signaling pathways of the four identified subtypes A) Analysis of the representative signaling pathways of the four subtypes. The signaling pathways provide information essential to the definition of the molecular levels of early-onset gastric cancer. B) The representative immune response signaling pathway of subtype 2. C) The representative cell migration signaling pathway of subtype 4.
2019 Korea University Summer Campus (KU ISC) KU ISC offers one semester's load of work condensed into 4 and 6 weeks, during which students can take credit-bearing courses and engage with world-class academics. As part of our summer program, we provide field trips for our participants to explore this amazing country and culture. • Program Period 6-week: June 25, 2019 – August 1, 2019 4-week: June 25, 2019 – July 18, 2019 • Application Period: January 2, 2019 - May 15, 2019 Please see the attachment for the further informations.
KU–KBSI-UNIST research team develops high-performance electrode catalysts for water-splitting Results published in leading journal Advanced Materials ▲ Dr. Aram Oh, Ho Young Kim, Dr. Hionsuck Baik, Prof. Sang Hoon Joo, Prof. Kwangyeol Lee (from left) Water electrolysis technology, which breaks down water to obtain hydrogen, is recognized as a clean technology that does not produce carbon dioxide or other pollutants. In particular, water electrolysis in acidic media has come under the spotlight for its high activity. However, the high cost and low durability of the iridium or ruthenium catalysts are obstacles to commercialization, but have been overcome thanks to a new electrode catalyst developed by a local research team. The team, comprised of members of Korea University (Prof. Kwangyeol Lee, Department of Chemistry), the Korea Basic Science Institute (Aram Oh and Hionsuck Baik), and the Ulsan National Institute of Science and Technology (Prof. Sang Hoon Joo and Ho Young Kim), fabricated a Pt/Ni/Ru nanocrystal, and utilized it as an electrode catalyst for water electrolysis in acidic media. With this proposed nanocrystal electrode catalyst, they succeeded in achieving the world best standard of activity and durability for water-splitting electrode catalysts. The team fabricated a core double-shell icosahedral Pt/Ni/Ru nanocrystal by applying phase dissociation to a nanoparticle alloy comprised of multiple elements, and examined the structure and composition of the nanoparticles through double modified aberration-corrected transmission electron microscopy. After acid and heat treatment, they produced a new type of nanocrystal, consisting of a Ni/Ru-doped Pt core and a Pt/Ni-doped RuO2 frame shell. The proposed nanocatalyst featured catalytic activity 15 times higher than current commercial iridium catalysts. While commercial iridium catalysts only managed to retain 40% of their initial performance after 10 hours of operation, the proposed catalyst retained 90%, demonstrating its durability. The core and frame shell structure of the proposed catalysts minimizes the use of expensive metal, and has optimal area for high catalytic activity. Through the synergistic Pt/Ni/Ru relationship, the team achieved the world’s highest activity and durability for water electrolysis reactions. They were also able to examine the mechanism behind the formation of frame-type nanoparticles using the high spatial resolution (60 pm) transmission electron microscope owned by the Seoul center of KBSI. Professor Kwangyeol Lee said, “To commercialize this technology, we are conducting follow-up studies on the mass production of catalysts, and the extension of stable operation time. The catalytic activity and improved durability of unstable metal oxides doped with other elements can be applied to various catalytic systems related to energy and the environment, and thereby play a part in overcoming environmental issues.” Professor Sang Hoon Joo of UNIST said, “Further research will be conducted to study the principles behind the improved catalytic activity and durability of the new catalyst.” Supported by the National Research Foundation of Korea and KBSI, the study was published in the online version of Advanced Materials, a leading journal in nanoscience, chemistry and materials science, on October 26 under the title of “Topotactic Transformations in an Icosahedral Nanocrystal to Form Efficient Water‐Splitting Catalysts.” [Fig. 1] TEM image of the high-performance Pt/Ni/Ru nanocatalyst, and a schematic evaluating the performance of the electrode catalyst for water electrolysis [Fig. 2] Schematic of water electrolysis
International Academic Conference in Celebration of 30th Anniversary of Constitutional Court The Korea University School of Law held 2018 Korea-Germany International Conference In celebrating the 30th Anniversary of the establishment of the Korean Constitutional Court, the Korea University School of Law held the 2018 Korea-Germany International Conference on campus on Tuesday and Wednesday, November 6-7, in association with the Konrad Adenauer Foundation and the Constitutional Academic and Professional Association. At the Conference, participants discussed how faithfully the Constitutional Court is playing its role as a protector of the Constitution at the interstices of law and politics, and how the administration of justice should be reformed to ensure the independence of the judiciary. On November 6, the first discussion – titled “Judicial Assessments of Constitutionality and Democracy: Is the Constitutional Court a protector of the Constitution or a political player?”, and presided over by Professor Seung-ju Bang from Hanyang University Law School – started at 2p.m, with the opening speeches by Dean of the Korea University School of Law Soon-gu Myung and Director of the Korean office of the Konrad Adenauer Foundation Stefan Samse. Former Deputy Chief Justice of the German Federal Administrative Supreme Court and Former Deputy Chief Justice of the Berlin State Constitutional Court Michael Hund, currently an attorney at law, delivered the first presentation, titled “Judicial Assessments of Constitutionality and of Administrative Law in a Democracy: How Political is German Jurisprudence?” Comparing aspects of the Korean and German Constitutional Courts, Hund provided 12 theses which addressed two questions, namely the status under the German Constitution of trials held in the Constitutional and Administrative courts, and the extent to which these courts are political. The next speaker was Professor Seon-Taek Kim from the KU School of Law. In his presentation on “The Constitution and Judicial Assessments of Constitutionality: on the Border of Law and Politics,” he began by emphasizing the duality of the Constitution and the Constitutional Court due to the opposing pulls of the ideals of justice and of political philosophy and practicality. Touching upon historical cases of the tension between law and politics in the Korean judiciary's assessments of the constitutionality of certain actions or laws, he talked about the distinctive status, mission and structure of the Constitutional Court, and the limits on the adherence to the Constitution on the part of the judiciary itself. A follow-up discussion began at 4 p.m. after a short break. Professor Tae-ho Chung from Kyung Hee University Law School, Professor Sang Hie Han from Konkuk University Law School, Constitution Researcher at the Constitutional Court Ji-Hyun Kim, Professor Jung-in Yoon from the Korea University Legal Research Institute, Public Relations Officer at the Berlin Criminal Court Justice Lisa Jani, and Constitution Researcher at the German Federal Constitutional Court Dr. Philipp Wittmann shared their thoughts on the presentation. Justice Jani and Dr. Wittmann also elaborated on the ways in which the German Federal Constitutional Court has protected the nation’s democracy and the Constitution through its proceedings. Finally, there was an hour-long open Q&A session and wrap-up discussion from 5 to 6 p.m. before the Day 1 proceedings were concluded. On November 7, six Korean participants (including Professor Seung-ju Bang) and two German counterparts engaged in a round-table discussion on “The Independence of Judges and the Judicial Administration.” The Korean speakers addressed the current issue of the Supreme Court corruption scandal, in which a former justice is suspected of having been bribed to intentionally delay a trial and to press other judges to do the same, the potential, or – as many believe – likely, result of which might have generated unfavorable public opinion about the then government. The speakers also discussed the possible actions that should be taken to address valid concerns about the scandal. Dr. Wittman talked about the Distortion of Law Act, which stipulates that judges who commit crimes while in office and thereby fail to uphold justice be punished, as well as how the above-mentioned Korean judicial scandal is viewed in Germany. All participants at the conference shared fruitful ideas about how judges in Korea can secure their independence from external pressures, with reference to the case of Germany. “Korea is going through a challenging time due to its failures to meet the standards of a democracy operating under the rule of law,” Lawyer Jae-Young Kim said. “The kinds of thoroughgoing judicial reform discussed at this conference will hopefully help the nation overcome these problems.”